DNA/RNA Synthesis Activator

Deoxycytidine triphosphate-¹³C₉ (dCTP-¹³C₉ dilithium; 2′-Deoxycytidine-5′-triphosphate-¹³C₉) dilithium is ¹³C-labeled Deoxycytidine triphosphate (HY-101400). Deoxycytidine triphosphate (dCTP) is a nucleoside triphosphate that can be used for DNA synthesis. Deoxycytidine triphosphate has many applications, such as real-time PCR, cDNA synthesis, and DNA sequencing.

Deoxycytidine triphosphate-¹³C₉,¹⁵N₃ (dCTP-¹³C₉,¹⁵N₃ dilithium; 2′-Deoxycytidine-5′-triphosphate-¹³C₉,¹⁵N₃) dilithium is ¹³C and ¹⁵N-labeled Deoxycytidine triphosphate (HY-101400). Deoxycytidine triphosphate (dCTP) is a nucleoside triphosphate that can be used for DNA synthesis. Deoxycytidine triphosphate has many applications, such as real-time PCR, cDNA synthesis, and DNA sequencing.

Uridine-5'-diphosphate (UDP) sodium is an important nucleotide made of uracil, ribose, and a pyrophosphate group. Uridine-5'-diphosphate sodium is a potent, selective human P2Y₆ receptor native agonist (EC₅₀ = 300 nM; pEC₅₀ = 6.52). Uridine-5'-diphosphate sodium, an endogenous metabolite, catalyzes the glucuronidation of a wide array of substrates and is used in nucleic acid (RNA) biosynthesis.

LVV-hemorphin-7 is an Angiotensin IV receptor ligand and IRAP inhibitor (IC₅₀s: 17.6 nM for sheep adrenal IRAP; 5.0 nM for sheep cerebellum IRAP). LVV-hemorphin-7 inhibits the catalytic activity of IRAP. LVV-hemorphin-7 stimulates DNA synthesis. LVV-hemorphin-7 elicits a number of physiological effects, including cellular proliferation and memory enhancement.

IACS-4619 (compound 4) is a highly selective 2-aminopyrimidine-based MTH1 (MutT homolog 1) inhibitor (IC₅₀=0.2 nM). IACS-4619 inhibits MTH1 by blocking its hydrolysis of oxidized purine nucleotides such as 8-oxo-dGTP, thereby preventing MTH1 from inhibiting the incorporation of oxidized nucleotides into DNA. IACS-4619 significantly inhibits endogenous MTH1 activity in MTH1-overexpressing U2OS cells, but without antiproliferative or cytotoxic effects on various human cancer and normal cell lines. IACS-4619 can be used in oncology research related to the MTH1 target.

Preptin, an osteogenic peptide product of the pancreatic beta-cell, corresponds to Asp⁶⁹-Leu¹⁰² of pro-IGF-II.

ICR-191 dihydrochloride enhances Cisplatin (HY-17394)- DNA binding and sensitizes cells to cisplatin. ICR-191 dihydrochloride induces a significant increase in the expression of phosphorylated H2AX (γH2AX), particularly in DNA-replicating cells. ICR-191 dihydrochloride can be used for the study of leukemia.

Deoxythymidine-5'-triphosphate-¹³C₁₀,¹⁵N₂ dilithium (dTTP-¹³C₁₀,¹⁵N₂ dilithium) is the ¹³C, ¹⁵N-labeled Deoxythymidine-5'-triphosphate (HY-138615). Deoxythymidine-5'-triphosphate (dTTP) is a deoxyribonucleoside triphosphate and a thymidine analog, which serves as a direct precursor for DNA synthesis. Deoxythymidine-5'-triphosphate can be used for DNA amplification in the DNA polymerase chain reaction (PCR). Deoxythymidine-5'-triphosphate is also applicable to research related to diseases such as leukemia.

Petasites japonicus extract is the extract from Petasites japonicus with antioxidant, anti-inflammatory, anti-obesity, neuroprotective and anti-cancer effects. Petasites japonicus extract promotes osteoblast differentiation via up-regulation of Runx2 and Osterix in MC3T3-E1 cells.

BzDANP is a modulator of pre-miR-29a maturation by dicer. BzDANP shows much affinity to the bulged RNAs.

AV-153, a 1,4-dihydropyridine (1,4-DHP) derivative, is an antimutagenic. AV-153 intercalates to DNA in a single strand break and reduces DNA damage, stimulates DNA repair in human cells in vitro. AV-153 interacts with thymine and cytosine and has an influence on poly(ADP)ribosylation. AV-153 has anti-cancer activity.

Roxithromycin (Standard) is the analytical standard of Roxithromycin. This product is intended for research and analytical applications. Roxithromycin (RU-28965) is a semi-synthetic macrolide antibiotic.

Deoxythymidine-5'-triphosphate-¹⁵N₂,d₁₅ dilithium (dTTP-¹⁵N₂,d₁₅ dilithium) is the deuterated, ¹⁵N-labeled Deoxythymidine-5'-triphosphate (HY-138615). Deoxythymidine-5'-triphosphate (dTTP) is a deoxyribonucleoside triphosphate and a thymidine analog, which serves as a direct precursor for DNA synthesis. Deoxythymidine-5'-triphosphate can be used for DNA amplification in the DNA polymerase chain reaction (PCR). Deoxythymidine-5'-triphosphate is also applicable to research related to diseases such as leukemia.

Deoxycytidine triphosphate-¹⁵N₃,d₁₄ (dCTP-¹⁵N₃,d₁₄ dilithium; 2′-Deoxycytidine-5′-triphosphate-¹⁵N₃,d₁₄) dilithium is deuterium and ¹⁵N labeled Deoxycytidine triphosphate (HY-101400). Deoxycytidine triphosphate (dCTP) is a nucleoside triphosphate that can be used for DNA synthesis. Deoxycytidine triphosphate has many applications, such as real-time PCR, cDNA synthesis, and DNA sequencing.

5'-O-DMT-N6-Me-2'-dA is a nucleoside with protective and modification effects.

Silatrane is a functionalized reagent. Silatrane stimulates the biosynthesis of DNA and proteins. Silatrane functionalizes oligonucleotides. Silatrane is applicable to the finishing of glass fibers. Silatrane can be used in research related to malignant tumors.

PAICS-IN-1 is a PAICS inhibitor. PAICS-IN-1 inhibits the bifunctional enzyme catalyzing the 6th and 7th steps of the de novo purine pathway. PAICS-IN-1 can be used for the research of cancer.

Uridine-5'-diphosphate (UDP) disodium salt (Standard) is the analytical standard of Uridine-5'-diphosphate disodium salt (HY-W010832). This product is intended for research and analytical applications. Uridine-5'-diphosphate disodium salt is an important nucleotide made of uracil, ribose, and a pyrophosphate group. Uridine-5'-diphosphate disodium salt is a potent, selective human P2Y₆ receptor native agonist (EC₅₀ = 300 nM; pEC₅₀ = 6.52). Uridine-5'-diphosphate disodium salt, an endogenous metabolite, catalyzes the glucuronidation of a wide array of substrates and is used in nucleic acid (RNA) biosynthesis.